Sp-8-Br-PET-cGMPS

• Catalog Number: orb2646237
• Category: Small Molecules
• Description: Sp-8-Br-PET-cGMPS is a membrane-permeable PKG activator and an inhibitor of the membrane-permeable retinal cGMP-gated ion channels (cGMP-gated ion channel). It also serves as an activator for cGMP-dependent protein kinase I α and β. Resistant to mammalian cyclic nucleotide-dependent phosphodiesterases, Sp-8-Br-PET-cGMPS does not undergo metabolic side effects and exhibits stronger lipophilicity and permeability compared to Sp-8-pCPT-cGMPS. This compound is useful for investigating the role of the cGMP signaling pathway in the nervous system.
• Purity: 98.00%
• MW: 540.28
• CAS Number: 172806-21-2
• Formula: C₁₈H₁₅BrN₅O₆PS
• SMILES: BrC=1N(C2=C(N1)C(=O)N3C(N2)=NC(=C3)C4=CC=CC=C4)[C@H]5[C@H](O)[C@]6([C@](O5)(COP(=O)(S)O6)[H])[H]
• Storage: -20°C
• Note: For research use only