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SP-471P

SKU: orb1744185

Description

SP-471P is a potent inhibitor of dengue virus (DENV) protease, exhibiting half-maximal effective concentrations (EC50) of 5.9 μM for DENV1, 1.4 μM for DENV2, 5.1 μM for DENV3, and 1.7 μM for DENV4, with a cytotoxic concentration (CC50) greater than 100 μM. Additionally, SP-471P effectively reduces DENV viral RNA synthesis.

Research Area

Cell Biology, Infectious Disease & Virology, Molecular Biology

Images & Validation

Key Properties

CAS Number2768011-36-3
MW604.5
FormulaC33H26BrN5O2
SMILESBrC1=CC=CC(CN2C3=C(C=C(C4=CC(/C(N)=N/O)=CC=C4)C=C3)C5=C2C=CC(C6=CC(/C(N)=N/O)=CC=C6)=C5)=C1
TargetVirus Protease,Others,DNA/RNA Synthesis,Anti-infection

Storage & Handling

Storage-20°C
DisclaimerFor research use only
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Quality Guarantee

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Protocol Information

SP-471P (orb1744185)

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