Sp-2-Cl-cAMPS

SKU: orb2646062

Description

Sp-2-Cl-cAMPS is a potent and cell-permeable PKA agonist with notable antimalarial properties. It inhibits Plasmodium falciparum growth (EC50 = 4 µM) by binding to the PfPKAr regulatory subunit (Ki = 1.3 µM), making it a valuable tool for studying cAMP signaling in parasitology research.

Research Area

Infectious Disease & Virology, Signal Transduction

Key Properties

• CAS Number: 124854-63-3
• MW: 379.72
• Formula: C₁₀H₁₁ClN₅O₅PS
• SMILES: NC1=C2C(N(C=N2)[C@H]3[C@H](O)[C@]4([C@](O3)(COP(=O)(S)O4)[H])[H])=NC(Cl)=N1
• Target: PKA,Parasite

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

14102402