Sovilnesib

SKU: orb1303452

Description

Sovilnesib is a potent and selective inhibitor of the mitotic kinesin KIF18A. It is a valuable research tool for studying cell division and has shown anti-tumor activity in preclinical cancer models, supporting its investigation in oncology research.

Research Area

Signal Transduction

Key Properties

• CAS Number: 2410796-79-9
• MW: 564.65
• Purity: 99.57% (May vary between batches)
• Formula: C₂₆H₃₄F₂N₆O₄S
• SMILES: Cc1cc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC3)CC2)nc(n1)N1CCC(F)(F)CC1
• Target: Microtubule Associated,Kinesin
• Solubility: DMSO:150 mg/mL (265.65 mM);10% DMSO+90% Corn Oil:2.5 mg/mL (4.43 mM)

Bioactivity

• In Vitro:
  Sovilnesib is an inhibitor of the kinesin-like protein KIF18A.

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Sovilnesib, AMG 650, AMG650, AMG-650, Inhibitor, inhibit, Microtubule Associated, Microtubule/Tubulin, MicrotubuleAssociated, mitotic kinesin Kif18A

Compound Identifiers

PubChem CID

148163435