Sotuletinib dihydrochloride

SKU: orb1944510

Description

Sotuletinib (BLZ945) dihydrochloride is a potent, brain-penetrant CSF1R inhibitor (IC50 = 1 nM) that induces tumor cell apoptosis. It has demonstrated significant anti-tumor efficacy in murine models and is a valuable research tool for studying cancer and neurodegenerative diseases like ALS in both in vitro and in vivo settings.

Research Area

Signal Transduction

Key Properties

• CAS Number: 2222138-40-9
• MW: 471.4
• Formula: C₂₀H₂₄Cl₂N₄O₃S
• SMILES: N(C=1SC=2C(N1)=CC=C(OC=3C=C(C(NC)=O)N=CC3)C2)[C@H]4[C@H](O)CCCC4.Cl.Cl
• Target: c-Fms

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

138455086