SOS1/EGFR-IN-2

SKU: orb2695708

Description

SOS1/EGFR-IN-2 is a potent dual SOS1 and EGFR inhibitor with IC50 values of 8.3 nM and 14.6 nM, respectively. It shows robust antiproliferative activity in KRAS-mutant cancer cell lines and is a valuable chemical probe for studying oncogenic RAS/EGFR signaling pathways in vitro.

Research Area

Cardiovascular Research, Cell Biology, Signal Transduction

Key Properties

• MW: 490.52
• Formula: C₂₅H₂₉F₃N₄O₃
• SMILES: O=C(NC1=CC=C(Cl)C(Cl)=C1)C=2C=CC=CC2NS(=O)(=O)C=3C=CC=C(C3)N(=O)=O
• Target: Kras,Ras,EGFR

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

172652612