SOS1-IN-7

SKU: orb1687119

Description

SOS1-IN-7 (compound 18-p1) is a potent small molecule SOS1 inhibitor, demonstrating activity against SOS1-G12D (IC50 20 nM) and SOS1-G12V (IC50 67 nM). This research compound is a valuable tool for investigating KRAS-driven cancers in both cellular and animal models, aiding the study of RAS/MAPK pathway signaling.

Research Area

Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• CAS Number: 2755415-30-4
• MW: 462.46
• Formula: C₂₃H₂₅F₃N₄O₃
• SMILES: N([C@H](C)C1=C(F)C(C(F)F)=CC=C1)C2=C3C(=NC(=O)C(=C3)[C@]4(O)CC[C@@H](O)CC4)NC(C)=N2
• Target: Others,Ras

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

163322193