SOS1-IN-16

SKU: orb1944316

Description

SOS1-IN-16 (Comp 54) is a potent and selective SOS1 inhibitor with an IC50 of 7.2 nM. It also inhibits CYP3A4 (IC50 = 8.9 µM with testosterone). This compound is a valuable chemical probe for investigating SOS1/KRAS-dependent signaling pathways in cancer research, applicable in both cellular and biochemical studies.

Research Area

Metabolism Research, Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• CAS Number: 2930763-85-0
• MW: 552.59
• Formula: C₃₀H₃₁F₃N₄O₃
• SMILES: N([C@H](C)C1=C(F)C(C(CO)(F)F)=CC=C1)C=2C3=C(C=CC(=C3)C4=CC(CC(N(C)C)=O)=C(OC)C=C4)N=C(C)N2
• Target: Cytochromes P450,Ras

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

168476141