Sorbifolin

SKU: orb1981822

Description

Sorbifolin is a potent natural flavone glycoside that acts as a myeloperoxidase (MPO) inhibitor with an IC50 of 19.2 nM. It demonstrates radical scavenging activity and is used in research on oxidative stress and inflammation in both in vitro and in vivo experimental models.

Research Area

Metabolism Research

Key Properties

• CAS Number: 23130-22-5
• MW: 300.26
• Purity: 98.42% (May vary between batches)
• Formula: C₁₆H₁₂O₆
• SMILES: OC1=C2C(OC(=CC2=O)C3=CC=C(O)C=C3)=CC(OC)=C1O
• Target: Glutathione Peroxidase,Free radical scavengers
• Solubility: DMSO:80 mg/mL (266.44 mM)

Bioactivity

• Target IC50:
  Myeloperoxidase:19.2 nM
• In Vitro:
  Sorbifolin exhibited free radical scavenging activity after 30 minutes of action, with IC₅₀ values of 5.7 μM and 13.5 μM against ABTS radicals and DPPH radicals, respectively .
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Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

3084390