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Catalog Number | orb1982765 |
---|---|
Category | Small Molecules |
Description | Sonrotoclax is a potent, orally active inhibitor of Bcl2, demonstrating effective cell-killing activity against a range of lymphoma and leukemia cell lines [1]. |
Purity | 98.82% |
MW | 890.10 |
Biological Activity | Sonrotoclax (BGB 11417) is a selective inhibitor targeting the WT and G101V mutants of Bcl-2 with potential antitumor activity for the study of lymphoma and leukemia. |
CAS Number | 2383086-06-2 |
Formula | C49H59N7O7S |
SMILES | CC(C1=C(C=CC=C1)[C@H]2N(CCC2)C3CC4(CCN(C5=CC(OC6=CN=C(NC=C7)C7=C6)=C(C=C5)C(NS(=O)(C8=CC([N+]([O-])=O)=C(C=C8)NC[C@@H]9CC[C@@](O)(CC9)C)=O)=O)CC4)C3)C |
Storage | -20°C |
Note | For research use only |