Sodium salicylate

SKU: orb1310710

Description

Sodium salicylate

Research Area

Cell Biology, Immunology & Inflammation, Metabolism Research, Neuroscience, Signal Transduction

Key Properties

• CAS Number: 54-21-7
• MW: 160.11
• Purity: >99.99% (May vary between batches)
• Formula: C₇H₅NaO₃
• SMILES: [Na+].Oc1ccccc1C(=O)[O-]
• Target: Endogenous Metabolite,Autophagy,COX,S6 Kinase,NF-κB,Apoptosis
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (12.49 mM);DMSO:50 mg/mL (312.29 mM);Ethanol:< 1 mg/mL (insoluble or slightly soluble);H2O:29 mg/mL (181.13 mM)

Bioactivity

• In Vitro:
  Sodium salicylate acts as non-steroidal anti-inflammatory drug (NSAID), and induces apoptosis in cancer cells and also necrosis. Sodium salicylate inhibits the activation of NF-kappa B, and also inhibits NF-kappa B-dependent transcription from the Ig kappa enhancer and the human immunodeficiency virus (HIV) long terminal repeat (LTR) in transfected T cells. Sodium salicylate also induces apoptosis via p38 MAPK and inhibits TNF-induced JNK/stress-activated protein kinase activation.
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Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Ribosomal S6 Kinase (RSK), S6 Kinase, S6K, S6Kinase, Salicylic acid, Salicylic acid sodium, Salicylic acid sodium salt, Sodium, Sodium salicylate, Sodium Salicylate, COX, COX-1, Cyclooxygenase, COX-3, 2-Hydroxybenzoic acid, 2-Hydroxybenzoic acid sodium, 2-Hydroxybenzoic acid sodium salt, Autophagy, Apoptosis, Inhibitor, inhibit, Nuclear factor-κB, Nuclear factor-kappaB, NaSal, NF-κB, NFkB, NF-kB, NFκB, Endogenous Metabolite

Compound Identifiers

PubChem CID

16760658