Sodium L-ascorbyl-2-phosphate

SKU: orb1224307

Description

L-Ascorbicacid, 2-(dihydrogen phosphate), sodium salt (1:3) can be used as antioxidant.

Key Properties

• CAS Number: 66170-10-3
• MW: 322.05
• Purity: >98% (HPLC)
• Formula: C₆H₆Na₃O₉P
• SMILES: O=C(C(OP([O-])([O-])=O)=C([O-])O1)[C@H]1[C@@H](O)CO.[Na+].[Na+].[Na+]
• Target: Vitamin
• Solubility: Soluble in Water

Bioactivity

• In Vitro:
  L-Ascorbic acid 2-phosphate (0.1-1.5 mM; 2 to 3 weeks with medium exchange every 2 to 3 days) trisodium significantly stimulates cell growth, whereas addition of l-Ascorbic acid (Asc) achieves only weak growth stimulation. A combination of Asc-2P and bFGF significantly increases cell growth, but supplementation with EGF and/or insulin does not have any additional effect. L-Ascorbic acid 2-phosphate (50 μM-250 μM) trisodium is needed for the effective osteogenic differentiation of human adipose stem cells (hASCs), and higher concentrations of AsA2-P results in increased runx2 expression and ALP activity. The highest proliferation, ALP activity and runx2 expression is achieved with 150 μM AsA2-P and 10 nM dexamethasone (Dex), and 250 μM AsA2-P and 5 nM Dex.

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

2-Phospho-L-ascorbic acid trisodium salt

Quick Database Links

Gene Symbol

Vitamin