Sodium Houttuyfonate

SKU: orb1297058

Description

Sodium Houttuyfonate

Research Area

Infectious Disease & Virology, Signal Transduction

Key Properties

• CAS Number: 83766-73-8
• MW: 302.36
• Purity: ≥95% (May vary between batches)
• Formula: C₁₂H₂₃NaO₅S
• SMILES: CCCCCCCCCC(=O)CC(O)S(=O)(=O)[O-].[Na+]
• Target: Antifungal,Antibacterial,NF-κB
• Solubility: H2O:3.33 mg/mL (11.01 mM);DMSO:17.86 mg/mL (59.07 mM)

Bioactivity

• In Vivo:
  Sodium houttuyfonate has been shown to protect against cationized bovine serum albumin (C-BSA)-induced glomerulonephritis in BALB/C mice through the suppression of the urine protein, morphological character and monocyte chemotactic protein 1 (MCP-1).
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• In Vitro:
  Treatment with sodium houttuyfonate results in an increase in the expression of c-Fos protein in macrophages, while the phosphorylation level of extracellular signal-related kinase 1/2 (ERK1/2) is not affected by the treatment.
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Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Sodium Houttuyfonate, Bacterial, NFkB, NFκB, NF-kB, NF-κB, Fungal, Houttuynin sodium Bisulfite, Houttuynin sodium bisulfite

Compound Identifiers

PubChem CID

23663544