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Catalog Number | orb1304008 |
---|---|
Category | Small Molecules |
Description | Sodium dichloroacetate |
CAS Number | 2156-56-1 |
Purity | 99.32% |
MW | 150.92 |
SMILES | C(C(=O)[O-])(Cl)Cl.[Na+] |
Formula | C2HCl2NaO2 |
Biological Activity | Sodium dichloroacetate (BCA) , a specific inhibitor of pyruvate dehydrogenase kinase (PDK) with IC50 values of 183 and 80 μM for PDK2 and PDK4 respectively, has been shown to derepress a mitochondrial potassium-ion channel axis, trigger apoptosis in cancer cells, and inhibit tumor growth. |
Storage | -20°C |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |