Sodium Aescinate

SKU: orb1304609

Description

Sodium Aescinate, the sodium salt of escin, is a bioactive saponin compound purified from the seeds of Aesculus wilsonii. It is widely used in pharmacological research for its anti-inflammatory and anti-edema properties, investigated in both in vitro cellular assays and in vivo models of vascular permeability and inflammation.

Research Area

Cardiovascular Research, Epigenetics & Chromatin, Signal Transduction

Key Properties

• CAS Number: 20977-05-3
• MW: 1123.21
• Purity: 95.17%
• Formula: C₅₄H₈₃NaO₂₃
• SMILES: [Na+].CC(OC(C)=O)C(C)C(=O)OC[C@@]12[C@@H](O)[C@H]3O[C@@H]1C[C@]1(C)C(=CC[C@@H]4[C@@]5(C)CC[C@H](O[C@@H]6O[C@@H]([C@@H](O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O)[C@H](O)[C@H]6O[C@@H]6OC[C@@H](O)[C@H](O)[C@H]6O)C([O-])=O)[C@@](C)(CO)[C@@H]5CC[C@@]14C)[C@@H]2CC3(C)C
• Target: HIF,NF-κB
• Solubility: DMSO:250 mg/mL (222.58 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

NF-κB, Nuclear factor-κB, Nuclear factor-kappaB, inhibit, Inhibitor, Escin sodium, Escin sodium salt, HIF-1α, Sodium Aescinate

Compound Identifiers

PubChem CID

139600352