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SNIPER(ABL)-058

SKU: orb1987735

Description

SNIPER(ABL)-058, a compound that links Imatinib (ABL inhibitor) with a derivative of LCL161 (IAP ligand) through a linker, effectively decreases BCR-ABL protein levels, achieving a half-maximal degradation concentration (DC50) of 10 μM.

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Key Properties

CAS Number2222354-61-0
MW1150.39
FormulaC62H75N11O9S
SMILESC([C@@H](NC([C@@H](NC)C)=O)C1CCCCC1)(=O)N2[C@@](CCC2)(C3=NC(C(=O)C4=CC(OCCOCCOCCOCC(=O)N5CCN(CC6=CC=C(C(NC7=CC(NC=8N=C(C=CN8)C=9C=CC=NC9)=C(C)C=C7)=O)C=C6)CC5)=CC=C4)=CS3)[H]
TargetSNIPERs,Bcr-Abl,Others

Storage & Handling

Storage-20°C
DisclaimerFor research use only
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Protocol Information

SNIPER(ABL)-058 (orb1987735)

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