SNIPER(ABL)-050

SKU: orb1987736

Description

SNIPER(ABL)-050 is a bifunctional degrader conjugate comprising Imatinib (an ABL kinase inhibitor) linked to an IAP ligand. This PROTAC-like molecule induces degradation of the BCR-ABL oncoprotein and is a valuable tool for investigating targeted protein degradation in chronic myeloid leukemia (CML) research, both in cellular and animal models.

Research Area

Cardiovascular Research, Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• MW: 1213.47
• Formula: C₆₈H₈₄N₁₂O₉
• SMILES: CC1=CC=C(NC(C2=CC=C(CN3CCN(C(COCCOCCOCCNC([C@H](C(C4=CC=CC=C4)C5=CC=CC=C5)NC([C@H]6N(C([C@@H](NC([C@H](C)NC)=O)C7CCCCC7)=O)CCC6)=O)=O)=O)CC3)C=C2)=O)C=C1NC8=NC=CC(C9=CC=CN=C9)=N8
• Target: Bcr-Abl,SNIPERs,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

138377563