SNIPER(ABL)-039

• Catalog Number: orb1987740
• Category: Small Molecules
• Description: SNIPER(ABL)-039, conjugating Dasatinib (ABL inhibitor) to an LCL161 derivative (IAP ligand) with a linker, induces the reduction of BCR-ABL protein with a DC50 of 10 nM. IC50s are 0.54 nM for ABL, 10 nM for cIAP1, 12 nM for cIAP2, and 50 nM for XIAP.
• Target: Others
• MW: 1114.77
• CAS Number: 2222354-29-0
• Formula: C₅₄H₆₈ClN₁₁O₉S₂
• SMILES: C([C@@H](NC([C@@H](NC)C)=O)C1CCCCC1)(=O)N2[C@@](CCC2)(C3=NC(C(=O)C4=CC(OCCOCCOCCOCC(=O)N5CCN(CC5)C=6C=C(NC=7SC(C(NC8=C(C)C=CC=C8Cl)=O)=CN7)N=C(C)N6)=CC=C4)=CS3)[H]
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.