SN50

SKU: orb1708506

Description

SN50 is a cell-permeable peptide inhibitor that blocks NF-κB nuclear translocation by mimicking the p50 subunit's nuclear localization sequence. It has demonstrated protective effects in rat models of ventilator-induced lung injury, suppresses pro-inflammatory mediators like IL-1β and TNF-α, and promotes M2 microglial polarization in research applications.

Research Area

Immunology & Inflammation, Metabolism Research, Signal Transduction

Key Properties

• Target: NF-κB,Glutathione Peroxidase,MAPK,IL Receptor
• CAS Number: 213546-53-3
• MW: 2781.5
• Purity: 99.91% (May vary between batches)
• Formula: C₁₂₉H₂₃₀N₃₆O₂₉S
• SMILES: C([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](C)N)=O)C)=O)C(C)C)=O)C)=O)CC(C)C)=O)CC(C)C)(=O)N1[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(=O)N2[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(=O)N3[C@H](C(O)=O)CCC3)CCSC)=O)CC(C)C)=O)CCCCN)=O)CCC(N)=O)=O)CCCNC(=N)N)=O)CCCCN)=O)CCCNC(=N)N)=O)CCC(N)=O)=O)C(C)C)=O)CCC2)C)=O)CC(C)C)=O)CC(C)C)=O)C)=O)CC(C)C)=O)CC(C)C)=O)C(C)C)=O)C)=O)CCC1

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

NF-κB, NFκB, NFkB, NF-kB, SN50, SN-50, SN 50

Compound Identifiers

PubChem CID

16209942