SN38-PAB-Lys(MMT)-oxydiacetamide-PEG8-N3

SKU: orb1943621

Description

SN38-PAB-Lys(MMT)-oxydiacetamide-PEG8-N3 is a click chemistry ADC linker-payload conjugate featuring an azide group for bioorthogonal conjugation via CuAAC or SPAAC. This construct enables the targeted delivery of the potent topoisomerase I inhibitor SN38, facilitating the synthesis of ADCs for preclinical in vitro and in vivo cancer research.

Key Properties

• CAS Number: 1373170-36-5
• MW: 1478.64
• Formula: C₇₈H₉₅N₉O₂₀
• SMILES: C(NCCCC[C@@H](C(NC1=CC=C(COC(O[C@@]2(CC)C3=C(C(=O)N4C(=C3)C=5C(C4)=C(CC)C=6C(N5)=CC=C(O)C6)COC2=O)=O)C=C1)=O)NC(COCC(NCCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-])=O)=O)(C7=CC=C(OC)C=C7)(C8=CC=CC=C8)C9=CC=CC=C9
• Target: Drug-Linker Conjugates for ADC

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

168476137