SN38-COOH

SKU: orb2279057

Description

SN38-COOH is the active metabolite of irinotecan, a topoisomerase I inhibitor that blocks DNA and RNA synthesis. It is a key payload for constructing antibody-drug conjugates (ADCs) and is widely used in cancer research for both in vitro cytotoxicity assays and in vivo efficacy studies.

Key Properties

• CAS Number: 2170118-23-5
• MW: 492.48
• Formula: C₂₆H₂₄N₂O₈
• SMILES: O(C(CCC(O)=O)=O)[C@@]1(CC)C2=C(C(=O)N3C(=C2)C=4C(C3)=C(CC)C=5C(N4)=CC=C(O)C5)COC1=O
• Target: Drug-Linker Conjugates for ADC

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

162446870