SN-398

SKU: orb2564427

Description

SN-398 is a potent camptothecin-derived antitumor agent that acts as a topoisomerase I (Topo I) inhibitor, stabilizing the Topo I-DNA complex to induce lethal DNA breaks. It demonstrates enhanced antiproliferative activity in vitro, such as in HeLa cell assays, and is a valuable tool for studying Topo I-targeted cancer therapies.

Research Area

Molecular Biology

Key Properties

• CAS Number: 124623-00-3
• MW: 410.40
• Formula: C₂₂H₁₉FN₂O₅
• SMILES: O=C1N2C(C=3C(C2)=C(CC)C=4C(N3)=CC(F)=C(O)C4)=CC5=C1COC(=O)[C@@]5(CC)O
• Target: Topoisomerase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

10386840