SN-011

SKU: orb1298339

Description

SN-011 (GUN35901) is a demethylated analog of DUN99845 functioning as a STING pathway inhibitor. It is utilized in research to suppress STING signaling, providing a tool for investigating STING-mediated diseases in both cellular and animal models.

Research Area

Immunology & Inflammation

Key Properties

• CAS Number: 2249435-90-1
• MW: 462.49
• Purity: 98.22% (May vary between batches)
• Formula: C₂₅H₁₉FN₂O₄S
• SMILES: Oc1ccc(NC(=O)c2ccc(cc2)-c2ccccc2)cc1NS(=O)(=O)c1ccc(F)cc1
• Target: STING
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.32 mM);DMSO:150 mg/mL (324.33 mM)

Bioactivity

• Target IC50:
  STING signaling:76 nM (IC50)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

GUN 35901, GUN35901, GUN-35901, ERIS, inflammatory, MPYS, inhibit, Inhibitor, MITA, CDN, cyclic dinucleotide, autoimmune, [1,1'-Biphenyl]-4-carboxamide, N-[3-[[(4-fluorophenyl)sulfonyl]amino]-4-hydroxyphenyl]-, TMEM173, STING, Stimulator of Interferon Genes, SN 011, SN011, SN-011

Compound Identifiers

PubChem CID

138005721