Autophagy,Histone Methyltransferase Antibody

SKU: orb1744373

Description

SMYD3-IN-2 is a potent and selective SMYD3 inhibitor with an IC50 of 0.81 µM, which induces lethal autophagy to inhibit gastric cancer cell proliferation, as shown in BGC823 cells (IC50 = 0.75 µM). This compound is a valuable chemical probe for studying SMYD3's role in oncology, supporting both in vitro and in vivo cancer research.

Research Area

Cell Biology, Epigenetics & Chromatin

Key Properties

• MW: 505.36
• Formula: C₂₆H₂₁BrN₂O₄
• SMILES: C1[C@@H]2[C@H]([C@]3(C4=CC=CC=C4NC3=O)O[C@@]2(C(=O)N1CC5=CC=CC=C5)O)C6=CC=C(C=C6)Br
• Target: Histone Methyltransferase,Autophagy

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

166642573