SMU-C68

SKU: orb3136502

Description

SMU-C68 is a highly selective small molecule agonist of the TLR1/2 heterodimer (EC50=0.009 μM). It activates the NF-κB and MAPK pathways, leading to the release of pro-inflammatory cytokines such as TNF-α and IL-1β. SMU-C68 holds potential for cancer research applications.

Research Area

Immunology & Inflammation, Signal Transduction

Key Properties

• CAS Number: 2677039-75-5
• MW: 411.54
• Formula: C₂₁H₂₁N₃O₂S₂
• SMILES: O=C(OC(C)C)C1=C(SC2=C1CCC2)NC(=S)NC3=CC=CC4=NC=CC=C43
• Target: p38 MAPK,NF-κB,TLR

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

p38 MAPK,NF-κB,TLR