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SMU-C409

SKU: orb3175033

Description

SMU-C409 is a TLR1/2 agonist with an EC50 of 65 nM in HEK-Blue hTLR2 cells. It activates the TLR1/2–MyD88–NF-κB pathway, inducing TNF-α/IL-1β secretion and strongly activating immune cells, resulting in antitumor immunomodulatory effects. Exhibiting low toxicity in vitro, SMU-C409 is useful for cancer immunology research.

Research Area

Cell Biology, Immunology & Inflammation, Signal Transduction

Images & Validation

Key Properties

TargetInterleukin,MyD88,TNF,NF-κB,TLR

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information