SMTIN-T140

SKU: orb1744414

Description

SMTIN-T140 (compound 6a) is a potent TRAP1 inhibitor (IC50 = 1.646 µM) that exerts anticancer effects by disrupting mitochondrial function, increasing ROS, and activating AMPK. It has demonstrated significant in vivo antitumor efficacy in a PC3 prostate cancer xenograft model without observable toxicity.

Research Area

Epigenetics & Chromatin, Immunology & Inflammation, Metabolism Research, Signal Transduction

Key Properties

• CAS Number: 2851532-40-4
• MW: 718.02
• Formula: C₃₆H₃₄BrClFN₅OP+
• SMILES: C1=CC=C(C=C1)[P+](CCCCCCN2C3=C(N=C(N=C3Cl)N)N(C2=O)CC4=C(C=C(C=C4)Br)F)(C5=CC=CC=C5)C6=CC=CC=C6
• Target: HSP,AMPK,Reactive Oxygen Species

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

163409182