SMS 121

SKU: orb3029115

Description

SMS 121 is a novel CD36 inhibitor that impairs fatty acid uptake and cell viability in acute myeloid leukaemia (AML) cells.

Research Area

Signal Transduction

Key Properties

• CAS Number: 949875-48-3
• MW: 355.38
• Purity: 98.29% (May vary between batches)
• Formula: C₂₀H₂₁NO₅
• SMILES: O=C(O)COC1=CC=C(C=CC(=O)C2=CC=C(C=C2)N(C)C)C=C1OC
• Target: Integrin
• Solubility: 50% PEG300+50% Saline:10 mg/mL (28.14 mM);DMSO:10 mg/mL (28.14 mM)

Bioactivity

• Target IC50:
  KG-1 cells:156 µM
• In Vitro:
  Methods: KG-1 cells were treated with SMS 121 (0-400 µM, 72 hours), and cell viability was measured by ATP assay. Results: SMS 121 inhibited KG-1 cell viability with an IC50 value of 156 µM.
  Read more...

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

SMS121

Quick Database Links

Gene Symbol

Integrin