SMO-IN-3

SKU: orb1686656

Description

SMO-IN-3 is a potent small molecule inhibitor of the smoothened (SMO) receptor within the Hedgehog signaling pathway, exhibiting an IC50 of 34.09 nM. It demonstrates anti-proliferative activity against the Daoy medulloblastoma cell line in vitro, supporting its use as a research tool for studying Hh-driven cancers.

Research Area

Pharmacology & Drug Discovery, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 2376914-71-3
• MW: 499.5
• Formula: C₂₇H₂₅F₄N₃O₂
• SMILES: C(=O)(C1=C(NC2=CC=CC=C2)C=CC=C1)N3CCC(N(C(=O)C4=C(C(F)(F)F)C=C(F)C=C4)C)CC3
• Target: Others,Hedgehog/Smoothened,Smo

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

152520884