SMO-IN-1

SKU: orb1688141

Description

SMO-IN-1 (Compound 15) is a bioavailable, orally active inhibitor of the Smoothened (SMO) receptor with an EC50 of 89 nM against Sonic Hedgehog (Shh) signaling. This tool compound is used in both in vitro and in vivo studies to investigate the Hedgehog pathway's role in development and disease.

Research Area

Stem Cell & Developmental Biology

Key Properties

• CAS Number: 1126365-66-9
• MW: 398.46
• Formula: C₂₄H₂₂N₄O₂
• SMILES: N(C(=O)C1=CC=C(OCC2=CC=CC=N2)C=C1)C=3C=C(C=CC3C)C=4N=CN(C)C4
• Target: Smo,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

70684298