SMIP004

SKU: orb1307738

Description

SMIP004

Research Area

Cell Biology, Protein Biochemistry

Key Properties

• CAS Number: 143360-00-3
• MW: 205.3
• Purity: 99.86%
• Formula: C₁₃H₁₉NO
• SMILES: CCCCC1=CC(C)=C(NC(C)=O)C=C1
• Target: E1/E2/E3 Enzyme,Apoptosis
• Solubility: DMSO:100 mg/mL (487.09 mM)

Bioactivity

• In Vivo:
  In SCID mice, SMIP004 effectively inhibits the growth of prostate and breast cancer xenografts .
• In Vitro:
  SMIP004 reduces the levels of positive cell cycle regulators upregulates cyclin-dependent kinase inhibitors. It also causes G1 arrest, inhibition of colony formation in soft agar, and cell death .

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

SKP2 E3 ligase, SMIP 004, SMIP004, SMIP-004, Ubiquitin activating enzyme, Ubiquitin conjugating enzyme, Ubiquitin ligase, Inhibitor, E3Enzyme, E3 Enzyme, E2Enzyme, E3 ligating enzyme, inhibit, Apoptosis, E1/E2/E3 Enzyme, E1 Enzyme, E1 activating enzyme, E1Enzyme, E2 conjugating enzyme, E2 Enzyme

Compound Identifiers

PubChem CID

2747581