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Catalog Number | orb1303469 |
---|---|
Category | Small Molecules |
Description | SMI-16a |
CAS Number | 587852-28-6 |
Purity | 97.06% |
MW | 263.31 |
SMILES | C(=C1SC(=O)NC1=O)C2=CC=C(OCCC)C=C2 |
Formula | C13H13NO3S |
Biological Activity | SMI-16a (PIM1/2 Kinase Inhibitor VI) , a cell-permeable thiazolidinedione compound, acts as an effective, ATP-competitive inhibitor against Pim-1/2 kinases (IC50: 150/20 nM) while exhibiting little or no activity against a panel of 57 other kinases (≤18% inhibition at 5 μM). |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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