SMARCA2-IN-10

SKU: orb3172868

Description

SMARCA2-IN-10 (Compound 4) is a highly selective SMARCA2 ATPase domain inhibitor (IC50=17.676 μM) that induces death in SMARCA4-deficient tumor cells. It can be used to study SMARCA4-mutant non-small cell lung cancer, small cell ovarian cancer, and melanoma.

Research Area

Epigenetics & Chromatin

Key Properties

• CAS Number: 82131-85-9
• MW: 496.47
• Purity: 99.99% (May vary between batches)
• Formula: C₂₈H₂₀N₂O₇
• SMILES: O=C(O)C=1C=CC=CC1C(=O)NC2=CC=C(OC3=CC=C(C=C3)NC(=O)C=4C=CC=CC4C(=O)O)C=C2
• Target: Epigenetic Reader Domain

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Epigenetic Reader Domain