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Catalog Number | orb2277219 |
---|---|
Category | Small Molecules |
Description | SMAP-18, an 18-amino acid residue peptide amide, is a biologically active truncated variant of Sheep myeloid antimicrobial peptide-29 (SMAP-29). It retains potent antimicrobial activity against Pseudomonas strains, other Gram-negative bacteria, and multidrug-resistant pathogens. Notably, SMAP-18 exhibits increased cell selectivity relative to the parent peptide SMAP-29 due to its reduced hemolytic activity while maintaining its antimicrobial efficacy. |
CAS Number | 1629248-30-1 |
Purity | 98.00% |
MW | 2061.53 |
SMILES | [C@@H](CC1=CC=C(O)C=C1)(NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@H](CC2=CN=CN2)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@H](CCCNC(=N)N)N)=O)=O)CC(C)C)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CC(C)C)=O)=O)CCCNC(=N)N)=O)CCCCN)=O)[C@H](CC)C)=O)C)=O)=O)=O)C(C)C)=O)CCCCN)=O)CCCCN)=O)C(NCC(N)=O)=O |
Formula | C93H165N35O18 |
Biological Activity | SMAP-18, an 18-amino acid residue peptide amide, is a biologically active truncated variant of Sheep myeloid antimicrobial peptide-29 (SMAP-29). It retains potent antimicrobial activity against Pseudomonas strains, other Gram-negative bacteria, and multidrug-resistant pathogens. Notably, SMAP-18 exhibits increased cell selectivity relative to the parent peptide SMAP-29 due to its reduced hemolytic activity while maintaining its antimicrobial efficacy. |
Storage | -20°C |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |