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SM-164 Hydrochloride (957135-43-2 free base)

SM-164 Hydrochloride (957135-43-2 free base)

Catalog Number: orb1708514

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Catalog Numberorb1708514
CategorySmall Molecules
DescriptionSM-164 Hydrochloride (957135-43-2 free base)
Purity98%
MW1157.88
SMILESC[C@H](NC)C(N[C@H]1CCCC[C@](CC[C@H]2C(N[C@@H](C3=CC=CC=C3)C4=CN(CCCCC5=CC=C(CCCCN6N=NC([C@@H](NC([C@@H]7CC[C@@](CCCC[C@@H]8NC([C@@H](NC)C)=O)([H])N7C8=O)=O)C9=CC=CC=C9)=C6)C=C5)N=N4)=O)([H])N2C1=O)=O.Cl
FormulaC62H85ClN14O6
Biological ActivitySM-164 Hydrochloride is a cell-permeable Smac mimetic compound. SM-164 binds to XIAP protein containing both the BIR2 and BIR3 domains(IC50 value of 1.39 nM) and functions as an extremely potent antagonist of XIAP.
Storage-20°C
NoteFor research use only
Expiration Date12 months from date of receipt.