δ-Sleep Inducing Peptide

SKU: orb1300066

Description

Delta sleep-inducing peptide (DSIP) is a neuropeptide known for its antioxidant and anxiety-reducing effects. It is utilized in neuroscience research to study sleep regulation, stress responses, and neuroprotection in both in vitro and in vivo experimental models.

Research Area

Metabolism Research

Key Properties

• CAS Number: 62568-57-4
• MW: 848.81
• Purity: 92.36% (May vary between batches)
• Formula: C₃₅H₄₈N₁₀O₁₅
• SMILES: CC(NC(=O)C(N)Cc1c[nH]c2ccccc12)C(=O)NCC(=O)NCC(=O)NC(CC(O)=O)C(=O)NC(C)C(=O)NC(CO)C(=O)NCC(=O)NC(CCC(O)=O)C(O)=O
• Target: Others,Antioxidant
• Solubility: DMSO:10 mM

Bioactivity

• In Vivo:
  Delta-Sleep Inducing Peptide(DSIP) and DSIP-12 significantly (*P<0.05 and **P<0.01) increased in delta and theta frequency bands and decreased the incidence, mean seizure grade and duration of metaphit convulsions. Suggest that DSIP and DSIP-12 may be considered as potential antiepileptics in the animal model.
• Animal Research:
  The rats divided in four groups received (i.p.): saline; metaphit; metaphit+DSIP; and metaphit+DSIP-12, respectively. Metaphit-treated animals displaying seizure in eight previous tests received DSIP or DSIP-12 and afterwards audiogenic stimuli were applied at hourly intervals for the next 30 h. The animals were exposed to sound stimulation 60 min after metaphit administration and further on at hourly intervals. Incidence and severity of seizures were behaviorally analyzed. Selected EEGs and power spectra were recorded and analyzed.

Storage & Handling

• Storage: keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

δSleep Inducing Peptide, Δ-Sleep Inducing Peptide, δ-Sleep Inducing Peptide, δ Sleep Inducing Peptide, Antioxidant, DSIP, Delta-Sleep Inducing Peptide, Inhibitor, inhibit

Compound Identifiers

PubChem CID

3623358