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SKLB-11A

SKU: orb3135234

Description

SKLB-11A is a potent allosteric agonist of SIRT3 (sirtuin 3). It activates signaling pathways associated with autophagy (autophagy), helps prevent mitochondrial dysfunction, and improves cardiac function in models of Doxorubicin-induced cardiotoxicity as well as myocardial ischemia/reperfusion.

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Key Properties

CAS Number433953-86-7
MW350.35
FormulaC19H15FN4O2
SMILESO=C(OC)C=1C=2N=C3C=CC=CC3=NC2N(C1N)CC4=CC=C(F)C=C4
TargetSirtuin,Autophagy

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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SKLB-11A (orb3135234)

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