SJF-1528 hemihydrate

SKU: orb3134490

Description

SJF-1528 hemihydrate is the hemihydrate form of SJF-1528. It acts as an EGFR PROTAC degrader, showing activity in OVCAR8 cells with wild-type EGFR and in HeLa cells with exon 20 Ins mutant EGFR, with DC50 values of 39.2 nM and 736.2 nM, respectively. Additionally, SJF-1528 hemihydrate degrades HER2.

Images & Validation

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Key Properties

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Formula	C₅₅H₅₇ClFN₇O₈S.1/2H₂O
Target	EGFR,PROTACs

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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EGFR,PROTACs

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