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SjDX5-271

SKU: orb2942727

Description

SjDX5-271 is a 3 kDa peptide inhibitor of the TLR4/MyD88/NF-κB pathway. It demonstrates anti-inflammatory effects by inducing cell polarization, mitigating liver inflammation, and providing protection in murine models of hepatic ischemia-reperfusion injury. This makes it a valuable research tool for studying innate immunity and inflammatory liver diseases.

Research Area

Immunology & Inflammation, Signal Transduction

Images & Validation

Key Properties

TargetNF-κB,TLR
CAS Number2767993-76-8
MW3336.52
FormulaC137H215N47O49S
SMILESC([C@H](CC1=CC=CC=C1)NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC2=CC=C(O)C=C2)N)=O)CCCCN)=O)CC(N)=O)=O)CC(C)C)=O)=O)=O)CCC(N)=O)=O)CCC(N)=O)=O)CCC(N)=O)=O)CO)=O)=O)CO)=O)CO)=O)CCC(N)=O)=O)=O)CCC(N)=O)=O)(=O)N3[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(=O)N4[C@H](C(N[C@H](C(N[C@@H](CCC(N)=O)C(O)=O)=O)CCC(N)=O)=O)CCC4)CCCNC(=N)N)=O)CCC(N)=O)=O)CCC(N)=O)=O)CCC(N)=O)=O)CCC(N)=O)=O)CCSC)=O)CCC(N)=O)=O)=O)CO)=O)CCC3

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

Protocol Information

Protein Handling and Storage Guide
Protein Handling Guide
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