SJ-C1044

SKU: orb2665270

Description

SJ-C1044 is an orally active pan-RAF inhibitor with additional activity against VEGFR2, TIE2, and CSF1R. It suppresses tumor growth by inhibiting the MAPK pathway and modulates the tumor immune microenvironment, making it a candidate for research in colorectal cancer models both in vitro and in vivo.

Research Area

Cardiovascular Research, Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• CAS Number: 2121503-76-0
• MW: 561.41
• Formula: C₂₅H₁₄F₇N₇O
• SMILES: O=C(NC1=CC(=CC=C1F)NC2=NC=CC=C2C=3N=CN=C4N=CNC43)C=5C=C(C=C(C5)C(F)(F)F)C(F)(F)F
• Target: MEK,Raf,Ras,VEGFR,ERK,Tie-2,c-Fms

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

130321895