SIRT6 activator 12q

SKU: orb1744873

Description

12q is a potent, selective, and orally active SIRT6 activator with an IC50 of 0.58 μM, showing >300-fold selectivity over other sirtuins. It exhibits anticancer properties in vitro by inhibiting proliferation and migration, inducing apoptosis, and causing G2/M cell cycle arrest, supporting research in oncology and aging.

Research Area

Cell Biology, Epigenetics & Chromatin, Molecular Biology

Key Properties

• CAS Number: 2601734-99-8
• MW: 454.52
• Purity: 98.53% (May vary between batches)
• Formula: C₃₁H₂₂N₂O₂
• SMILES: O=C(NC(C=1C=CC=CC1)C=2C=CC=CC2)C3=CC(=NC=4C=CC=CC43)C=5OC=6C=CC=CC6C5
• Target: Sirtuin

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

156013743