SIRT6 activator 12q

SKU: orb1744873

Description

12q is a potent, selective, and orally active SIRT6 activator with an IC50 of 0.58 μM, showing >300-fold selectivity over other sirtuins. It exhibits anticancer properties in vitro by inhibiting proliferation and migration, inducing apoptosis, and causing G2/M cell cycle arrest, supporting research in oncology and aging.

Research Area

Cell Biology, Epigenetics & Chromatin, Molecular Biology

Key Properties

• CAS Number: 2601734-99-8
• MW: 454.52
• Formula: C₃₁H₂₂N₂O₂
• SMILES: C(NC(C1=CC=CC=C1)C2=CC=CC=C2)(=O)C=3C4=C(N=C(C3)C5=CC=6C(O5)=CC=CC6)C=CC=C4
• Target: Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

156013743