SIRT5 inhibitor 9

SKU: orb2278352

Description

Compound 14 (SIRT5 inhibitor 9) is a substrate-competitive inhibitor exhibiting moderate selectivity for SIRT5 with an IC50 of 4.07 µM. This tool compound is used in cancer research to investigate SIRT5's role in metabolism and tumorigenesis in both cellular and animal models.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 3054055-26-1
• MW: 561.06
• Purity: 98.68% (May vary between batches)
• Formula: C₂₄H₂₉ClN₈O₄S
• SMILES: O=C(O)CCNC(=S)NCCCNC=1N=C(N=C(N1)NC=2C=CC=CC2Cl)NC=3C=C(OC)C=C(OC)C3
• Target: Sirtuin

Bioactivity

• Target IC50:
  SIRT5: 4.07 μM

Storage & Handling

• Storage: store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

168679701