SIRT1/2/3-IN-1

SKU: orb1982518

Description

SIRT1/2/3-IN-1 is a potent, selective, and cell-permeable pan-sirtuin inhibitor with IC50 values of 0.54 µM (SIRT1), 0.253 µM (SIRT2), and 0.72 µM (SIRT3). It is a valuable chemical probe for investigating sirtuin biology in cancer research, applicable in both cellular and biochemical assays.

Research Area

Epigenetics & Chromatin, Molecular Biology

Key Properties

• CAS Number: 2413212-06-1
• MW: 934.18
• Formula: C₄₆H₆₃N₉O₈S₂
• SMILES: C(N[C@H](C(N[C@H]1CC=2C=CC(=CC2)OCCCCCNC(=O)[C@H](CCSC)NC1=O)=O)CCCCNC(C)=S)(=O)[C@@H]3CC=4C=CC(=CC4)OCCCC(=O)N[C@@H](CC5=CN=CN5)C(=O)N3
• Target: Others,Sirtuin

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

156018427