Sirt1/2-IN-2

SKU: orb2277854

Description

Sirt1/2-IN-2 (hsa55) is a dual SIRT1/2 inhibitor with IC50 values of 1.8 μM and 2.4 μM, respectively. It increases acetylation of p53 and α-tubulin, inhibits cell proliferation, and induces apoptosis in human leukemia cells in vitro, making it a useful research tool for studying sirtuin biology and cancer.

Research Area

Cell Biology, Epigenetics & Chromatin, Molecular Biology

Key Properties

• CAS Number: 670267-73-9
• MW: 398.46
• Formula: C₁₈H₁₄N₄O₃S₂
• SMILES: N(S(=O)(=O)C1=CC=CC=C1)C=2C3=C(C(O)=C(SC=4NC=NN4)C2)C=CC=C3
• Target: Apoptosis,Sirtuin

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

2133777