Sirt1/2-IN-1

SKU: orb1687800

Description

Sirt1/2-IN-1 is a potent inhibitor of SIRT1 and SIRT2, with additional activity against SIRT3, leading to α-tubulin hyperacetylation. It demonstrates significant anticancer effects in vitro and is a valuable chemical probe for studying sirtuin biology in cancer and aging-related research.

Research Area

Epigenetics & Chromatin, Molecular Biology, Signal Transduction

Key Properties

• CAS Number: 2402779-21-7
• MW: 420.93
• Formula: C₂₂H₁₃ClN₂OS₂
• SMILES: O=C1N2C(C3=C(C=4C(S3)=CC=C(Cl)C4)N=C2SC1)C5=CC6=C(C=C5)C=CC=C6
• Target: Sirtuin,Others,Microtubule Associated

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

155550829