Simvastatin Acyl-β-D-glucuronide

SKU: orb1690511

Description

Simvastatin Acyl-β-D-glucuronide is a major metabolite of Simvastatin and a potent competitive inhibitor of HMG-CoA reductase with a Ki of 0.2 nM. This inhibitor is a valuable research tool for studying statin metabolism, drug-drug interactions, and the pharmacological activity of metabolites in both in vitro enzymatic assays and in vivo models.

Research Area

Metabolism Research

Key Properties

• CAS Number: 463962-56-3
• MW: 612.71
• Formula: C₃₁H₄₈O₁₂
• SMILES: [H][C@]12[C@H](C[C@@H](C)C=C1C=C[C@H](C)[C@@H]2CC[C@@H](O)C[C@@H](O)CC(=O)O[C@@H]1O[C@@H]([C@@H](O)[C@H](O)[C@H]1O)C(O)=O)OC(=O)C(C)(C)CC
• Target: Drug Metabolite,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

92132235