Simufilamum Dihydrochloride Monohydrate

SKU: orb2815282

Description

Simufilam (PTI-125) is an oral small molecule that selectively binds and reverses pathogenic conformations of filamin A in Alzheimer's disease. It reduces key AD pathologies, including Aβ42 aggregation and tau hyperphosphorylation, with efficacy demonstrated from picomolar concentrations in vitro using post-mortem AD brain tissue.

Key Properties

• CAS Number: 2375909-85-4
• MW: 350.28
• Formula: C₁₅H₂₅Cl₂N₃O₂
• SMILES: O=C1N(C2(CCN(CC2)C)NC1)CC3=CC=CC=C3.Cl.Cl.O

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

155603443