Simotinib hydrochloride

SKU: orb1691627

Description

Simotinib hydrochloride is a potent and selective oral EGFR tyrosine kinase inhibitor with an IC50 of 19.9 nM. It demonstrates significant antitumor activity in vitro and has shown efficacy in preclinical in vivo models of EGFR-driven cancers.

Research Area

Cardiovascular Research, Signal Transduction

Key Properties

• CAS Number: 1538617-88-7
• MW: 537.41
• Formula: C₂₅H₂₇Cl₂FN₄O₄
• SMILES: Cl.COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCN1CC2(CC2)C2(C1)OCCO2
• Target: EGFR,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

76853547