Simepdekinra

SKU: orb3134936

Description

Simepdekinra (Compound 221) is a potent IL-17A modulator with IC50 values ≤10 nM for IL-17A/A HEK-Blue cells and 10–100 nM for IL-17A/F HEK-Blue cells, suitable for studying psoriasis, ankylosing spondylitis, and psoriatic arthritis.

Research Area

Immunology & Inflammation

Key Properties

• CAS Number: 2978700-29-5
• MW: 667.81
• Purity: 99.96% (May vary between batches)
• Formula: C₃₅H₅₀FN₇O₅
• SMILES: [C@H]([C@H](NC(=O)C=1N(CC)N=CC1)C(NC2=C(F)C=C([C@@H]([C@H](C(=O)N3C[C@@H](C)N(C)CC3)NC([C@@H](OC)C)=O)C)C=C2)=O)(C4CC4)C5CC5
• Target: IL Receptor

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

IL Receptor