PF-07899895

SKU: orb2665422

Description

PF-07899895 is a potent and selective salt-inducible kinase (SIK) inhibitor, exhibiting IC50 values of 1.2 nM, 0.9 nM, and 1.8 nM against SIK1, SIK2, and SIK3, respectively. This tool compound is useful for investigating SIK signaling in immunology, metabolism, and cancer research in both cellular and in vivo models.

Research Area

Signal Transduction

Key Properties

• CAS Number: 3033846-10-2
• MW: 417.53
• Purity: 99.81% (May vary between batches)
• Formula: C₂₃H₂₃N₅OS
• SMILES: N#CC1=CC=CC2=NC=C(C=3C=C(OCC4(N)CCCCC4)C(C#N)=C(SC)C3)N12
• Target: SIK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

171101962